Being Regular with follow ups and Hospital visits are very important in making the transplant a success.
Organ Transplantation is amazing. However our bodies don't easily accept transplant organs, and medication are needed to help prevent any transplant rejections and ease transplant side effects.
Your immune system is your body's defense against foreign invaders like bacteria or viruses. Unfortunately the immune system cannot tell the difference between a harmful invader and your transplant organ and will try to reject it.
Organ Rejection is dangerous because it can permanently damage your new organ. That is why your transplant team has prescribed anti rejections medicines as part of long term therapy.
Anti Rejection medication (also called immuneossppressants) help you to prevent your body from rejecting your organ transplant by slowing down your immune system. There are a variety of anti rejection medication available after an organ transplant and each works in a different way to suppress the body's immune response.
Your transplant team will determine which combination of medicines is right for you may alter you medication regimen.
The important thing is making sure that your doctor knows exactly what you are taking and to always check your anti rejection medication to ensure it's the one doctor has prescribed.
Therapeutic Drug monitoring (TDM) is the measurement of medication concentrations in blood.
TDM aims at improving patient care by adjusting the dose of drugs which can show the improved outcome of the drug in the general or special populations.
For some drugs maintaining this steady state is not as simple as giving a standard dose of medication. Each person will absorb metabolize utilize and eliminate drugs at different rates based upon their age general state of health , genera tic makeup and the interference of other medications that they are taking . These rates may change over time and vary from day to day. Changes in the rate may also occur in various disease states or through interaction with other medications.
Many of the drugs that require therapeutic monitoring are taken for lifetime. They must be maintained steady concentrations year after year while the person ages and goes through life events that may alter that individual therapeutic level including pregnancies temporary illness, infections, emotional and physical stresses, accidents and surgeries.
Therapeutic drug monitoring follows these changes and accommodates them. It identifies patient non compliance ( when the person does not take the medication regularly as prescribed and the effect of drug interaction which may cause drug concentrations that are of higher or lower than expected at a given dosage and helps to personize a dose to fit the specific needs of a patient.
Along with tests such as BUN creatinine and liver function tests monitoring can help identify decreases in the efficiency of the dysfunctions in the body ability to metabolize and eliminate therapeutic drugs. Testing may also determine how a medication interacts with other necessary drugs.
Did you know that anti rejection drugs aims to prevent rejection of your transplant organ can increase the risk for infection? Some may also cause stomach problem or other side effects. Ask your doctor if taking anti infective/ or anti ulcer medications may help you.
Despite the important role medications play in helping people healthy, studies show that not all Transplant recipients take their medication as prescribed. This is a scary fact because stopping even skipping a single dose - without guidance from your doctor is very dangerous.
As with some medications immunosuppressive treatment has side effects. But with a little planning and some help from your transplant team you can learn to manage some of these side effects. We suggest that you talk with your transplant team about the following conditions.
After an organ transplant there is a possibility that you may develop high blood pressure ( also called hyper tension ) and or high cholesterol due to immunosuppressive therapy . However there are ways to manage it including
Talk to your transplant team right away if you are experiencing any side effects. Your team can help you manage these side effects and may explore altering or switching your medications.
Some anti rejection medicines can cause high blood sugar and have been associated with the development of onset disabilities. Over weight transplant recipients or those with a family history of adult onset diabetes appear to be at higher risk for developing diabetes.
Call your transplant team right away if you are often very thirsty have to urinate more than usual have blurred vision or feel confused , these may be signs of high blood sugar. Early treatment can prevent complications. Adjusting the dose of anti rejection drugs or changing medications may help blood sugar levels return to normal. Never change your dosing or medication on your own. Talk to your Doctor who will decide what is right for you.
Certain medication may cause unwanted changes in the way you look, including weight gain, acne or a puffy ("moon-faced") appearances. Some medications can cause increased gum size or the growth of unwanted hair on the face or body while other are associated with unwanted hair loss.
Talk to your doctor about any side effects that concern you It May Be possible to help control these effects by changing doses of medicines.
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